Journal article
Association of depression with mortality in an elderly treated hypertensive population
EK Chowdhury, M Berk, MR Nelson, LMH Wing, CM Reid
International Psychogeriatrics | CAMBRIDGE UNIV PRESS | Published : 2019
Abstract
Background: Both elevated blood pressure and/or depression increase the risk of cardiovascular disease and mortality. This study in treated elderly hypertensive patients explored the incidence of depression, its association (pre-existing and incident) with mortality and predictors of incident depression. Methods: Data from 6,083 hypertensive patients aged ≥65 years enrolled in the Second Australian National Blood Pressure study were used. Participants were followed for a median of 10.8 years (including 4.1 years in-trial) and classified into: "no depression", "pre-existing" and "incident" depression groups based on either being "diagnosed with depressive disorders" and/or "treated with an an..
View full abstractGrants
Awarded by Department of Health and Aged Care, Australian Government
Funding Acknowledgements
We are indebted to the participants, study staff, data management centers, and ANBP2 Management Committee. The Management Committee consists of the following members: LMH Wing (Chair), CM Reid, LJ Beilin, MA Brown, GLR Jennings, CI Johnston, JJ McNeil, JE Marley, TO Morgan, P Ryan, J Shaw (deceased), MJ West, and G MacDonald. ANBP2 was supported by the Australian Commonwealth Department of Health and Aging; the National Health and Medical Research Council of Australia (grant 546272); and Merck Sharp & Dohme, Australia. CMR is supported by a Senior Research Fellowship from NHMRC (grant 1045862). The funders had no role in the study design, data collection, and analysis, or the decision to publish.